ROLE OF TRANSTHYRETIN LEVELS IN INDIAN CHILDREN AND ADOLESCENTS.
Reports from different parts from India suggested a rising trend prevalence in overweight and obesity among children and adolescents. The serum transthyretin and its correlation with biochemical parameters were analysed in 296 children and adolescents (103 control 96 obese, 97 overweight) of age group 10-17 years. Clinical and anthropometric parameters were also evaluated in all the children. The levels of serum transthyretin were measured by immuno turbidimetric assay. One of the major observations of this study was no significant differences of serum transthyretin between the groups and there was no association between serum transthyretin and Apo AI, Apo B and Lp(a) levels among the study groups. Therefore, the available information suggests that transthyretin levels were not affected by overweight and obesity related inflammation.
Keywords: Transthyretin, Overweight, Obesity.