EXTENT OF SURGICAL RESECTION IN MANAGEMENT OF CYSTOSARCOMA PHYLLODES: A RETROSPECTIVE CASE STUDY OF 48 PATIENTS.

Abstract

Introduction: Phyllodes tumors accounts for less than 1% of breast neoplasm. Displaying a broad range of clinical and pathological behavior, phyllodes tumors should be regarded as a spectrum of fibroephithelial neoplasms rather than a single entity. At one extreme, malignant phyllodes tumors, if inadequately treated, have a propensity for rapid growth and metastatic spread. In contrast, benign phyllodes tumors are often indistinguishable from fibroadenomas can be cured by local surgery. It was associated with high recurrence rate.
AIM of the study: To study the patient /tumour charecteristics affecting the clinical outcomes and recurrence of phyllodes tumor.
Materials and Methods: Data was collected from the In Patient Department and Out Patient Department clinical records of 48 patients of phyllodes tumor who underwent Wide Local Excision/Mastectomy in Department of general surgery, VMMC & Safdarjung hospital between june 2016 to june 2018 and then followed up till june, 2019.
Results:- a total of 48 patients were operated with mean age of 39 years and mean size of 48mm. Histopathology assessment showed 19 (39.5%) were benign,25(52.08%) were borderline,4(8.33%) were malignant. Margin status was negative for 42(87.5%) and positive for 6 (12.5%). In the follow up, there were a total of 5 recurrences which were seen in margin positive (4/5) and malignant histopathology (3/5) patients.
Conclusion: phyllodes tumor require wide local excision with adequate margin which is key factor for prevention of recurrence of the same.
Keywords: phyllodes tumor, simple mastectomy, wide local excision (WLE).