ASSESSMENT OF MATERNAL CARDIAC FUNCTION AND REMODELING IN WOMEN WITH PRE-ECLAMPSIA

Abstract

Introduction: Pre-eclampsia is a multi system disorder which occurs after 20 weeks of pregnancy. Women with pre-eclampsia has diverse hemodynamic findings such as increased cardiac output, high vascular resistance and decreased myocardial contractility. Acute  pre-eclampsia is associated with significant higher prevalence of asymptomatic abnormal global left ventricular functional geometry and myocardial injury leading to subsequent higher rise heart failure ischemic and hypertensive heart disease and related mortality compared with uneventful pregnancy in later life.[1,2] It is associated with maternal cardiac remodelling and biventricular diastolic dysfunction . In this study we evaluated and compared cardiac functions (systolic and diastolic) and remodelling and left ventricular strain in women with pre-eclampsia and healthy women by performing maternal echocardiography.

Materials and Methods: In this study 50 patient of each group (Healthy women & women with preeclampsia) are taken after informed consent. All subjects were subjected to standard 2-D doppler Transthoracic echocardiography at rest. Various parameters of study recorded. The data thus collected and were analysis.

Results: Systolic and diastolic parameters were jeopardized in pre eclamptic women as compared to the healthy women. The difference in longitudinal strain between the two groups was statistically significant. No significant change was observed between circumferential and radial strain.

Conclusion: There are structural and functional changes in the cardiovascular dynamics in subjects with Pre-eclampsia. Maternal echocardiography if introduced in routine management protocol could help to identify women who are at high risk to develop complications.

Keywords: Cardiac remodeling, Pre-eclampsia, Transthoracic echocardiography