Role of Gentamicin Loaded Collagen on Compound Fracture Internal Fixation
Keywords:compound fracture, gentamicin loaded collagen, post operative infection
Introduction: In the today’s world with faster ways of transportation high velocity accidents and the compound fracture are increasing day by day producing a challenge preventing post operative wound infections after internal fixation of fracture.
Materials and Methods: 50 patients of compound fractures were included in the study and were randomly divided in 2 groups of 25 each . Both the groups undergone internal fixation with stainless steel implant and one group wound is closed with gentamicin loaded collagen in it and other group without it
Method: In both the groups same process of and lavage is used and fractures were fixed internally fixed . A group has 25 patients in which after internal fixation the gentamicin loaded collagen is placed inside and in B group after internal fixation wound is closed without gentamicin loaded collagen.
Results: In group A where Gentamicin loaded collagen was placed wound infection was there in 2 patients . In Group B were no gentamicin loaded collagen was used 9 patietns has infections. P value 0.0275
Discussion: After surgery wound is assessed for post operative infection on 2 nd post op day 14 day at 4 weeks 6 weeks 3 months and 6 months
Conclusion: The Author believe that use of gentamicin loaded collagen significantly reducing the chance of infection in compound fractures surgeries.
Keywords: compound fracture, gentamicin loaded collagen, post operative infection