RISK FACTORS ASSOCIATED WITH WORSENING OF ACUTE PANCREATITIS.

  • Neeraj Dhar Post DM Senior Resident, Department of Gastroenterology, SKIMS
  • Syed Mushfiq Shafi Senior Resident, Department of Gastroenterology, SKIMS
  • Jaswinder Singh Professor, Department of Gastroenterology, SKIMS
  • G.M. Gulzar Professor, Department of Gastroenterology, SKIMS
  • Altaf Hussain Shah Professor and HOD, Department of Gastroenterology, SKIMS
  • Mushtaq Ahmad Khan Professor, Department of Gastroenterology, SKIMS
  • Sajad Hamid Faculty, SKIMS MCH
Keywords: Obesity, Pancreatitis, Risk Factors

Abstract

Background: The aim of the present study was to investigate risk factors for developing more severe pancreatitis, including moderately severe (MSAP) and severe acute pancreatitis (SAP), in patients admitted with mild acute pancreatitis (MAP).

Material/Methods: This was a hospital based retrospective and prospective study conducted in the Department of Gastroentrology, SKIMS Soura,Srinagar, Kashmir for a period of 2 years w.e.f. September 2017 to September 2019  on patients of all age groups with clinical/Laboratory/imaging  findings suggestive of acute pancreatitis. The protocol of the study was approved by the Institutional Ethical Committee. Patients admitted with MAP to our hospital were included and prospectively evaluated. Possible risk factors for developing MSAP or SAP were Evaluated.

Results: Risk factors like BMI >25kg/m2 was observed in 61 (19.3%) patients with mild pancreatitis and 142 (42.5%) patients with moderate to severe pancreatitis. Waist circumference >100cm was observed in 23 (7.3%) and 129 (38.6%) patients of mild and moderate to severe pancreatitis. High blood sugar >200mg/dl was observed in 37 (11.7%) patients with mild pancreatitis and 152 (45.2%) patients with moderate to severe pancreatitis. 27 (8.5%) and 167 (50%) patients of mild and moderate to severe pancreatitis had hematocrit >44 whereas 13 (4.1%) patients with mild pancreatitis and 140 (41.9%) patients with moderate to severe pancreatitis had CRP >150mg/dl.

This table concluded that there is statistically significant association between high BMI >25 Kg/m2, waist circumference >100 cm, high blood sugar >200 mg /dl, hematocrit >44, CRP >150 mg/d and worsening of AP.

Conclusions: Significant risk factors for developing MSAP or SAP in patients admitted with MAP included BMI (≥25 kg/m2), APACHE-II (≥5), and blood glucose level on admission (>11.1 mmol/L). These factors should be used in the prediction of more severe pancreatitis in patients admitted with MAP.

Keywords: Obesity, Pancreatitis, Risk Factors

Published
2021-01-17
How to Cite
Dhar, N., Shafi, S. M., Singh, J., Gulzar, G., Shah, A. H., Khan, M. A., & Hamid, S. (2021). RISK FACTORS ASSOCIATED WITH WORSENING OF ACUTE PANCREATITIS. International Journal of Medical Science And Diagnosis Research, 5(1). https://doi.org/10.32553/ijmsdr.v5i1.742
Section
Articles