CORRELATION OF SERUM PHOSPHATE AND CAROTID INTIMAL MEDIAL THICKNESS IN PREDIALYSIS CHRONIC KIDNEY DISEASES PATIENTS

Abstract

BACKGROUND- The study attempted to correlate serum phosphate and carotid intimal medial thickness in pre dialysis CKD patients.

METHODS- This was a cross sectional case control study involving 70 CKD patients. They were compared with age and gender matched 30 controls. Serum phosphate and Carotid Intimal Medial thickness was done in all patients along with routine investigations.

RESULTS- Carotid intimal thickness correlated with serum phosphate. There was significant negative correlation between CIMT and eGFR. The association between serum phosphate and CIMT could be expressed as a mathematical equation.

CONCLUSIONS- serum phosphate estimation can be used as a surrogate marker to assess CIMT in CKD patients.

KEY WORDS: CKD, CIMT, eGFR, phosphate, pre-dialysis CKD patients