ORGANOPHOSPHORUS POISONING PRESENTING WITH ACUTE CORTICAL NECROSIS: A RARE COMPLICATION OF A COMMON DISORDER IN INDIAN SETTING
Organophosphorus poisoning presenting with Acute Cortical Necrosis : A Rare complication of a common disorder in Indian Setting
Organophosphorus poisoning in the form of insecticides and pesticides acts by inhibition of anticholinesterase activity at the neuromuscular junction leading to overstimulation of the nicotinic and muscarinic receptor. Renal involvement usually manifests as increased urination, urinary incontinence, strangury due to overstimulation of urinary bladder . Acute kidney injury in the form of acute cortical necrosis is an extremely rare complication of OP poisoning. Here we highlight a case 31 year old male who presented to Emergency with Dichlorvos poisoning with anuria due to cortical necrosis requiring hemodialysis with gradually improving renal function thus representing an uncommon complication of Organophosphorus poisoning thus making it as a rare and interesting presentation.
Keywords: Organophosphorus poisoning, Acute cortical necrosis, Granular casts