HISTOPATHOLOGY OF OVARIAN SEX-CORD STROMAL TUMOURS: A TERTIARY CARE STUDY IN INDIAN POPULATION

Abstract

Objective: To study the frequency, histopathology and clinical features of sex cord-stromal tumours of the ovary. Material and Methods: The present study was carried out in the department of pathology in a tertiary care centre for a period of five years, from July 2008 to July 2013. Results: The frequency of ovarian tumours was 2.77% among the gynecological specimens received during the same period. Sex cord-stromal tumours constituted 9.65% of the ovarian tumours. Maximum cases were seen above 60 years of age. Pain and mass in abdomen was the most common presenting symptom. Granulosa cell tumour (63.64%) was the most common sex cord-stromal tumour in our study. Two cases of fibrothecoma (18.18%), one each of fibroma (9.09%) and sclerosing stromal tumour (9.09%) were reported. Conclusion: Histopathology is a time-tested foundation for accurate diagnosis of sex cord-stromal tumours of the ovary. It aids in prompt institution of treatment.

Keywords: histopathology, sex cord-stromal tumours, ovary, granulosa cell tumour