TO STUDY A NOVEL CHSP 60 (CHLAMYDIAL HEAT SHOCK PROTEIN) ANTIBODY AS A POTENTIAL MARKER FOR C.TRACHOMATIS INDUCED COMPLICATIONS ESPECIALLY INFERTILITY.

Authors

  • Dr. Mrinangka Deb

Abstract

Most genital Chlamydial infections tend to be asymptomatic or present with minimal symptoms coupled with the occurrence of severe sequela in untreated patients makes the laboratory evaluation of great importance in the diagnosis of the disease. Chlamydial heat shock protein 60 (Chsp60) may be an important antigen involved in the immunopathogenesis of C. trachomatis associated complications especially in chronic infection.

The present study was designed to determine the prevalence of anti Chlamydial heat shock protein 60 (Chsp60) antibodies in women attending a OBGY outpatient department in a tertiary care hospital in Navi Mumbai and whether it could be used as a  potential marker for  detection of C.trachomatis induced complications A total of 100 female patients were enrolled for the study. Blood/serum samples were collected from all the patients. The patients were investigated for the presence of Anti Chsp60 antibody of Chlamydia trachomatis with the help of the Enzyme Linked Immunosorbant Assay (ELISA). Our study showed that use of Anti Chsp60 antibody could be considered as a potential marker for detection of C.trachomatis induced complications.

Keywords C.trachomatis, Chlamydial heat shock protein 60  (Chsp60), Enzyme Linked Immunosorbant Assay (ELISA).

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Published

2020-06-30

How to Cite

Dr. Mrinangka Deb. (2020). TO STUDY A NOVEL CHSP 60 (CHLAMYDIAL HEAT SHOCK PROTEIN) ANTIBODY AS A POTENTIAL MARKER FOR C.TRACHOMATIS INDUCED COMPLICATIONS ESPECIALLY INFERTILITY. International Journal of Medical Science And Diagnosis Research, 4(6). Retrieved from https://www.ijmsdr.com/index.php/ijmsdr/article/view/607

Issue

Vol. 4 No. 6 (2020)

Section

Articles