LACK OF ASSOCIATION OF HIGH-RISK HUMAN PAPILLOMAVIRUSES IN HEAD AND NECK SQUAMOUS CELL CARCINOMA
Abstract
Head and neck cancer (HNC) are reportedly the sixth most occuring common cancer diagnosed worldwide. Yearly it was noted that around 633,000 new cases were diagnosed with Head and Neck cancer in which around 355,000 cases resulted in mortality [1].
It encompases several types of malignant tumors of the upper aerodigestive tract, which includes from the vermilion border of the lips and extends upto the beginning of the esophagus. Majority of the malignanat tumors of the head and neck are squamous cell carcinomas (SCCs), while adenocarcinomas were known to appear in less cases. [2][3] The incidence rate varies according to geographic region and associated risk factors of differing severity. Recent literature survey showed the declining incidence of head and neck asquamous cell carcinomas (HNSCC) has been due to reduced tobacco consumption in industrialized countries.