STUDY OF CLINICO-RADIOLOGICAL PROFILE OF INTERSTITIAL LUNG DISEASE PATIENTS ATTENDING CRGH UJJAIN
Introduction: Interstitial lung diseases are heterogeneous group of disorders of the lower respiratory tract that are characterized by both acute and chronic inflammation and a generally irreversible and relentless process of fibrosis in the interstitium and the alveolar walls. This study was undertaken with the aim to study the clinical and radiological spectrum of ILDs presenting to a tertiary care centre.
Methodology: The present study was conducted in Department of Pulmonary Medicine, tertiary care centre, Ujjain on 25 patients over a period of one year. All those patients who were suspected as case of ILD on clinical and radiological ground were included. A detailed history along with occupational history was obtained and entered in a questionnaire. All patients were examined clinically and underwent basic investigations along with PFT, ChestXray and HRCT thorax.
Result: The mean age of patients was 53.68 years and majority (68%) patients belonged to 41 to 60 years of age. Shortness of breath was present in all 100% patients. Velcro crepts was present in 24 (96%) patients while rhonchi was seen only in 3(12%) patients. Among most of the ILD patients i.e 20 (80%) septal thickening was seen. Honey combing was seen in 14(56%) patients. It was more in male as compare to female and there was significant difference only for this pattern (P=0.010).
Conclusion: Interstitial lung disease must be suspected with the presence of specific symptoms, signs and further investigations like haematological parameters, PFT, chest X-ray and HRCT chest. In large number of cases, accurate diagnosis of Interstitial pulmonary fibrosis can be made without a surgical lung biopsy and with a high specificity (>90%) following detailed clinical and radiological assessment with the help of HRCT.
Keywords: PFT, ILD, CXR. CT thorax.