STUDY OF SERUM LIPID PROFILE LEVEL IN CORONARY ARTERY DISEASE PATIENTS AT TERTIARY CARE CENTER SHAHJAHANPUR, U.P.

Abstract

Background: India and other developing countries in South Asia are progressively facing alarming proportions of morbidity and mortality caused by coronary artery disease

Methods: 100 subjects aged between 30 to 60years, comprising of 50 normal control and 50 patients suffering from CAD were studied.

Result: The mean total cholesterol level was found to be 174.16±18.14 mg/dl with a range of 150-200 mg/dl present in normal subjects and mean concentration of cholesterol level was increased to 288.92±46.67 mg/dl in CAD patients. The mean HDL level was found to be 46.74±4.48 mg/dl with a range of 30-60 mg/dl present in normal subjects and mean concentration of HDL level was decreased to 40.28±6.44 mg/dl in CAD patients. The mean LDL level was found to be 110.16±18.14 mg/dl with a range of 80-150 mg/dl present in normal subjects and mean concentration of LDL level was increased to 184.34±42.08 mg/dl in CAD patients. The mean Triglyceride level was found to be 114.20±36.12 mg/dl with a range of 75-150 mg/dl present in normal subjects and mean concentration of Triglyceride level was increased to 166.24±66.14 mg/dl in CAD patients.

Conclusion: This cross sectional study showed that high serum cholesterol, LDL, triglyceride and low HDL cholesterol were clinically significant in all the age groups.

Key-words: Coronary artery disease (CAD), Cholesterol, Triglyceride, HDL.