Central Neurocytoma and its mimic- MR Spectroscopy to the rescue
Abstract
The purpose of this study was to discriminate supratentorial intraventricular subependymoma from central neurocytoma using magnetic resonance spectroscopy (MRS).Multi-voxel proton MRS using a 3T MR scanner from two subependymomas and three CNCs were evaluated. Automatically calculated ratios comparing choline (Cho), N-acetylaspartate (NAA), myoinositol (MI), and glycine (Gly) to creatine (Cr) were determined. Evaluation of Cr to unsuppressed water (USW) was also performed. Mann-Whitney Utest was carried out to test the significance of differences in the metabolite ratios. Detectability of lactate (Lac) and alanine (Ala) was evaluated.Histopathology was taken as gold standard.
Keywords: Central neurocytoma, Intraventricular tumor, MR Spectroscopy, Supratentorial intraventricular subependymoma .